CORDIS Project
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This project aims to develop new treatments for chronic hepatitis B virus infection and related liver cancer. By establishing a reverse genetic system using woodchuck hepatitis virus, it seeks to create attenuated vaccines and therapeutic tools to combat the virus and its associated diseases.
Despite effective vaccines, hepatitis B virus (HBV) infection remains a major health problem with 2 billion people infected worldwide.
Among them, 350 million are chronically infected, a major risk factor for development of hepatocellular carcinoma (HCC). A new and efficient treatment against chronic infection and HCC is strongly needed, and therefore it is important to understand HBV replication and persistence.
In the absence of a good model, woodchuck infection with woodchuck hepatitis virus…
FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA
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