CORDIS Project
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This project explores chromatin assembly and the dynamics of histone proteins during DNA replication. It aims to understand how chromatin states are inherited and their implications for cellular differentiation and cancer development through high-throughput measurement systems.
Chromatin assembly is a fundamental cellular process necessary for the maintenance of genome integrity and transcriptional programs.
Understanding the effect of DNA replication on histone protein dynamics is also a prerequisite for understanding the role of chromatin in epigenetic inheritance.
Epigenetic phenomena are thought to influence cellular differentiation and cancer formation, as well as the impact of environmental factors on early development and later predispositions to disease.
While…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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