CORDIS Project
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This project investigates the interactions between mammalian viruses and the RNA silencing machinery, focusing on the roles of cellular and viral microRNAs in regulating viral infections. It aims to identify miRNAs with antiviral or proviral properties and understand how viruses manipulate these pathways.
The importance of small non-coding RNAs is growing exponentially in modern biology.
They have recently emerged as critical regulators of gene expression.
Different classes of small RNAs have been defined, and among them micro (mi) RNAs, and small interfering (si) RNAs are the most studied.
Viruses interact extensively with the RNA silencing machinery.
Thus in plants and insects, they are directly targeted and degraded by Dicer proteins.
The situation is more complicated in mammals, where a more…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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