CORDIS Project
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This project investigates a newly identified process called Focal Axonal Degeneration, which contributes to axonal damage in Multiple Sclerosis. By using advanced imaging techniques, the research aims to understand the functional characteristics, molecular mechanisms, and potential therapeutic strategies to mitigate ax…
Multiple Sclerosis (MS) is an inflammatory CNS disease that affects more than 2.5 million individuals worldwide.
Damage to axonal connections determines the functional deficits of MS patients.
How axons are damaged in MS is only incompletely understood.
Using in vivo multiphoton imaging we have discovered a novel axon loss process that underlies axonal damage in experimental and human neuroinflammatory lesions.
We have termed this process Focal Axonal Degeneration (FAD). FAD is characterized by…
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
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