CORDIS Project
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The NeoGutChip project develops an innovative in vitro model to study the interactions between gut microbiota, immune cells, and the intestinal lining in infants. This model aims to enhance our understanding of how early dietary and microbial factors influence gut health and immune development in babies.
Developing a healthy host-microbiome symbiosis during the first 1000 days of human life is critical for lifelong health.
Despite its importance, our understanding is limited and derives from animal studies or associative human trials.
Therefore, there is a pressing need for an infant gut model to capture dynamic microbiome-epithelium-immune interactions in early life.
In NeoGutChip I will develop and validate a first-of-its-kind in vitro human Infant Gut-Microbiome-Immune-on-a-chip model (iGuMI)…
UNIVERSITEIT VAN AMSTERDAM
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