CORDIS Project
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This project investigates the mechanisms of nucleotide excision repair (NER) in bacteria and eukaryotes, focusing on the structural and biochemical characterization of protein complexes involved in the repair process. It aims to elucidate the details of how DNA damage is detected and corrected, which is crucial for mai…
DNA damage caused by chemical and physical factors can lead to detrimental effects to the cell and must be corrected.
One of the primary pathways to achieve this repair is nucleotide excision repair (NER).
In NER, the DNA damage is first located, a stretch of bases harboring the lesion is removed, and the gap is filled by a DNA polymerase.
The unique feature of NER is its ability to correct a wide spectrum of DNA modifications of different sizes and chemical structures.The aim of the project is…
INTERNATIONAL INSTITUTE OF MOLECULAR AN CELL BIOLOGY IN WARSAW
MIEDZYNARODOWY INSTYTUT BIOLOGII MOLEKULARNEJ I KOMORKOWEJ W WARSZAWIE
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