CORDIS Project
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This project aims to revolutionize enzyme design by applying network models to enhance their catalytic efficiency. By understanding enzyme dynamics and customizing mutations, it seeks to create enzymes for cost-effective production of specific drugs, benefiting various industries.
Billions of years of evolution have made enzymes superb catalysts capable of accelerating reactions by several orders of magnitude.
The underlying physical principles of their extraordinary catalytic power still remains highly debated, which makes the alteration of natural enzyme activities towards synthetically useful targets a tremendous challenge for modern chemical biology.
The routine design of enzymes will, however, have large socio-economic benefits, as because of the enzymatic advantages…
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