CORDIS Project
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This project investigates enteric neuropathy, a condition affecting gut function due to neuron dysfunction. It focuses on understanding the role of specific macrophages in supporting enteric neurons, aiming to identify therapeutic targets for treating gastrointestinal disorders linked to obesity, diabetes, and aging.
The gastrointestinal tract has the vital task to digest and absorb ingested food, a complex process requiring coordinated integration of motility, secretion, vascularization and absorption.
Thereto the gastrointestinal tract is equipped with its own nervous system, the enteric nervous system (ENS), capable of controlling gut function independently of input from brain or spinal cord.
Reduction in number or dysfunction of the neurons within the gut wall, also referred to as enteric neuropathy, sig…
KATHOLIEKE UNIVERSITEIT LEUVEN
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