CORDIS Project
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This project investigates how neuronal remodeling influences brain circuit architecture and behavior using the Drosophila Mushroom Body as a model. It aims to identify key molecules involved in this process and understand the effects of genetic changes on circuit function and behavior.
Neuronal remodeling is a conserved strategy to refine neural circuits during development.
Defects in remodeling have been associated with neuropsychiatric disorders, but direct mechanistic causality is lacking.
Despite its fundamental significance, how remodeling of neuronal processes affects circuit architecture and function, and how this ultimately shapes behavior, is not only unknown, but also extremely challenging to study in complex organisms.
Our lab is a world-leader in the molecular mech…
WEIZMANN INSTITUTE OF SCIENCE
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