CORDIS Project
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This project investigates the interplay between alternative splicing and RNA editing in the development of the mammalian central nervous system. It aims to uncover how these processes contribute to cellular complexity and potential neurological disorders.
A long-standing question in biology has been to determine how the mammalian central nervous system (CNS) achieves its dramatic cellular complexity and connectivity.
Notably, mechanisms increasing transcript diversity, particularly alternative splicing (AS) and RNA-editing, have critical roles in the mammalian CNS development and function.
However, it is still unclear whether the crosstalk between these two processes constitutes an additional RNA-mediated regulatory layer contributing to the comp…
FUNDACIO CENTRE DE REGULACIO GENOMICA
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