CORDIS Project
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This project investigates the role of RNA editing in age-related neurodegenerative diseases like amyotrophic lateral sclerosis and frontotemporal dementia. It focuses on understanding how ADAR enzymes regulate RNA modifications and their implications for neuronal health, aiming to identify potential therapeutic targets…
Age-related neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) or frontotemporal dementia (FTD), are a major public health problem since there is no effective treatment due to the poor understanding of the pathological processes involved in neuronal death. RNA editing, particularly A-to-I changes mediated by ADAR enzymes, stands as the most prevalent form of post-transcriptional RNA modification.
Emerging evidence indicates that the efficiency and pattern of RNA editing in t…
ASOCIACION INSTITUTO BIOGIPUZKOA
ASOCIACION INSTITUTO DE INVESTIGACION SANITARIA BIOGIPUZKOA
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Australia, Melbourne
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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