CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates how neurons coordinate growth and biosynthesis in response to axonal length. By studying the communication between axons and the cell nucleus, it aims to uncover mechanisms that regulate neuronal growth and may inform strategies for neural repair.
Neurons exhibit the most marked size differences and diversity in intrinsic growth rates of any class of cells.
How then can a neuron coordinate between biosynthesis rates in the soma and the growth needs of different lengths of axons?
The central hypothesis of this proposal is that neurons sense the lengths of the axonal microtubule cytoskeleton on an ongoing basis by bidirectional motor-dependent axon-nucleus communication, and that the oscillating retrograde signal generated by this mechanism…
WEIZMANN INSTITUTE OF SCIENCE
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
