CORDIS Project
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This project aims to understand the distribution mechanisms of Cajal-Retzius cells during brain development. It combines genetic analysis, imaging techniques, and innovative visualization methods to study cell interactions and the role of the transcription factor Ebf3.
Cell migration is a fundamental process during mammalian brain development since all neurons migrate to their final location.
Cajal-Retzius (CR) cells are transient neurons that control the laminar organization of the cerebral cortex and form a monolayer at its the surface.
It has been shown that CR cells are generated by focal sources surrounding the cerebral cortex and disperse on its surface.
However, how the monolayer distribution of CR cells is achieved during development and what cell cont…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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