CORDIS Project
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This project aims to develop a nano-electrode chip that allows for high-resolution stimulation and imaging of single neurons over extended periods. This technology will enhance the study of synaptic transmission and facilitate high-throughput drug screening using real neurons.
Cellular studies in neuroscience are hampered by the fact that in vitro cultures of primary neurons are complex, variable and heterogeneous, making studies on cultured neurons time consuming, labour intensive and not scalable.
Especially for single cell studies on synaptic transmission and cellular trafficking, this is a major limitation.
Both in academia and industry, mitotic cells are commonly used as a proxy for neurons (e.g. PC12 cells).
However, while being less variable and better scalable…
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Netherlands, Amsterdam
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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