CORDIS Project
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This project focuses on understanding the molecular mechanisms behind epilepsy by examining the interactions between RNA binding proteins and microRNAs. It aims to identify new therapeutic targets that could lead to effective treatments for epilepsy and related brain disorders.
Imbalances between excitatory and inhibitory neural networks are a hallmark of several brain disorders including epilepsy.
Current drug therapies for epilepsy are ineffective in a third of patients and none have disease-modifying effects.
It is of high priority, therefore, to understand molecular/ genetic mechanisms responsible for epilepsy development and identify novel targets.
The control of mRNA stability and translation is critical for proper neural network function.
Here, RNA binding prote…
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