CORDIS Project
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This project focuses on understanding neurodegenerative disorders by investigating how neuronal proteins respond to oxidative stress. It employs advanced protein engineering techniques to monitor changes in the neuronal proteome, aiming to identify new biomarkers and drug targets for early-stage treatments.
Neurodegenerative disorders are characterised by the progressive deterioration and loss of certain neuronal populations.
Distinct clinical features are associated with different diseases, but common fundamental processes have been identified.
One example of this is injury via oxidative stress.
The production of oxidative species is linked to mitochondrial dysfunction and inflammation, which have been demonstrated to occur early in these disorders.
Identifying the proteins that are involved in th…
EBERHARD KARLS UNIVERSITAET TUEBINGEN
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