CORDIS Project
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This project investigates the role of specific neurons in the brain's arcuate nucleus in regulating glucose levels. It aims to understand the molecular mechanisms influencing glucose sensitivity and their implications for obesity and diabetes.
Development of obesity and diabetes is the consequence of impaired glucose homeostasis regulation.
The hypothalamic area of the brain and more precisely the arcuate nucleus (ARC) plays a critical role in this regulation.
The ARC detects changes in blood glucose level and triggers appropriate physiological responses.
For instance, increased brain glucose level increases insulin secretion and decreases food intake.
Different populations of glucose sensitive neurons have been characterize in the AR…
INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
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