CORDIS Project
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This project investigates the role of the RNA-binding protein Staufen 2 in neurogenesis and its potential link to Alzheimer's disease. Using induced pluripotent stem cells and single-cell transcriptomics, it aims to uncover the gene and protein networks influenced by Staufen 2, contributing to our understanding of brai…
Neurogenesis is a crucial process by which new neurons are formed in the brain through the conversion of Neuronal stem cells (NPCs).
Altered neurogenesis has been identified in Alzheimer’s disease (AD), in both human brains and rodent models, yet the exact mechanism of the dysregulation is unknown.
Over the past few years, growing evidence indicates that RNA-binding proteins (RBPs) play a critical role to fine-tune neurogenesis and mediate cortical development in the mammalian brain.
Among thes…
FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE
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