CORDIS Project
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This project investigates how environmental enrichment influences brain plasticity and immune response. By studying the interaction between immune cells and microglia in mice, it aims to identify molecular targets that could enhance brain function and potentially provide therapeutic benefits for conditions like Autism.
Neuroplasticity is the essential ability of the brain to respond and adapt to extrinsic and intrinsic stimuli, and it is strongly influenced by the environment we live in.
Exposure to e nvironmental enrichment (EE) leads to neurological changes paralleled by changes in the immune system. EE promotes neurogenesis, neuroplasticity, and ameliorates neuroinflammation in both rodents and humans.
Microglia and brain T cells also adapt their phenotype and T cell number increases, suggesting a connecti…
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