CORDIS Project
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This project investigates the role of neutrophils in colorectal cancer, particularly in patients with microsatellite stable tumors. By utilizing advanced single-cell techniques, it aims to create a detailed map of neutrophil diversity and function, potentially leading to new therapeutic strategies that enhance immune r…
Colorectal cancer (CRC) is the second most common cause of cancer death with an alarming rising incidence among young individuals.
While the management of early-stage CRC has improved greatly, the median overall survival for patients with metastatic CRC is 30 months.
Immune checkpoint inhibitors (ICI) have revolutionized the treatment of advanced solid cancers, yet for CRC continue to lag behind, with the exception of 4% of patients with microsatellite instability.
In contrast, several studies h…
MEDIZINISCHE UNIVERSITAT INNSBRUCK
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