CORDIS Project
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This project investigates why certain neurons in the brain are more susceptible to damage in Alzheimer's disease. By modulating gene expression in specific neurons, the research aims to uncover mechanisms of neurodegeneration and identify potential therapeutic targets.
The aim of this action is to understand the mechanisms behind the susceptibility of enthorinal cortex II (ECII) neurons to neurofibrillary tangle (NFT) formation in Alzheimer´s disease.
To do so we will modulate the expression of the genes that according to NetWAS (Network-wide Association Study) are more directly involved in NFT formation in ECII neurons.
Understanding why the pathological lesions that lead to neurodegeneration appear earlier in some specific neurons of the human brain is one…
KAROLINSKA INSTITUTET
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THE ROCKEFELLER UNIVERSITY NOT FOR PROFIT CORPORATION
United States, New York
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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