CORDIS Project
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This project focuses on developing carbohydrate-oxidising enzymes to create a versatile toolkit for modifying carbohydrates. The goal is to produce bioactive compounds, including antimicrobial derivatives and health-beneficial sugars, using a sustainable and efficient biocatalytic process.
Carbohydrate-oxidising enzymes (COE) are a group of enzymes which are active on specific carbohydrates and can use molecular oxygen as a mild oxidant.
Oxidation is typically directed towards specific positions of the sugar ring.
Regioselectivity and substrate specificity relies on the architecture of active site, therefore the direct evolution approach in this project will allow to generate a toolbox of effective and regiospecific catalysts to modify various carbohydrate scaffolds.
Our aim is to…
UNIVERSIDADE NOVA DE LISBOA
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