CORDIS Project
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This project develops an advanced imaging technology called Hi-M that allows for the simultaneous detection of multiple DNA and RNA species in single cells within intact tissues. It aims to enhance data acquisition and analysis in genetics and genomics, making it applicable in fields like cancer research and neuroscien…
Next generation sequencing has led to revolutionary discoveries in the fields of genetics, genomics, epigenetics and transcriptional regulation.
The main limitation of this technology relies on the loss of spatial information:
NGS is unable to retrieve the organization of nucleic acids (DNA/RNA) in the cell or within the more complex structure of the tissue.
We have recently developed a novel imaging-based technology, Hi-M, that enables the simultaneous detection of tens of DNA and RNA species i…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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