CORDIS Project
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The NIR-NanoCAR project aims to develop a novel immunotherapy for pancreatic cancer using near-infrared light to activate thermosensitive liposomes and exosomes. This approach targets mutated KRAS and seeks to improve treatment efficacy while minimizing side effects.
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers with a 5-year survival rate under 10%.
Current treatments for PDAC are based on ineffective and unspecific drugs that cause hard side effects.
Besides, new T cell-based immunotherapies are toxic and unsuccessful in most solid tumors, including PDAC.
Activating KRAS mutations occur in almost all patients, but unfortunately, KRAS is difficult to target.
This discouraging situation highlights the need to design orthogonal and i…
UNIVERSIDAD DE GRANADA
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LABORATORIO IBERICO INTERNACIONAL DE NANOTECNOLOGIA LIN
Portugal, Braga
Type: Research institute
Activity type: Research Organisations
SME: No
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