CORDIS Project
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This project investigates the interactions between penicillin binding proteins in Neisseria meningitidis, a bacterium responsible for meningitis. By using various scientific methods, it aims to understand how these proteins affect the bacterium's structure and its ability to cause disease.
Neisseria meningitidis (Nm) is a leading cause of bacterial meningitis and septicemia worldwide with a high case-fatality rate.
Although penicillin remains the drug of choice in the treatment of IMD, an increasing number of meningococci with reduced susceptibility to penicillin have been emerging worldwide.
Reduces susceptibility or resistance to penicillin in meningococci is connected to alterations in penicillin binding protein 2, PBP2. PBPs are involved in the late stages of peptidoglycan (PG…
NARODOWY INSTYTUT LEKOW
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