CORDIS Project
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This project aims to develop a microfluidic model that replicates the blood-brain barrier for drug testing. By creating a more biologically relevant in vitro system, it seeks to improve the prediction of drug efficacy and safety in treating neurological disorders.
There is great need to develop safer and more biologically relevant models for drug screening.
Recent reports indicate that up to 20% of acute kidney complications can be linked to drug-induced nephrotoxicity and more than 40 molecules found to reduce Alzheimer’s Disease (AD)-related plaques in animal models were shown to be ineffective in AD patients.
It is increasingly evident that both in vitro and in vivo models being used to develop drugs have a limited capacity to predict the pathophysiolo…
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