CORDIS Project
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This project aims to identify and characterize epigenetic regulators in acute myeloid leukemia, focusing on their potential as drug targets. It utilizes advanced screening techniques to explore the role of these regulators in maintaining leukemic cells.
Acute myeloid leukemia is a hematopoietic malignancy characterized by the abnormal proliferation of immature myeloid cells.
The implementation of high-throughput sequencing revealed that somatic mutations in various epigenetic regulators represent a frequent pathogenic phenomenon in leukemogenesis.
This raised optimism for the development of new therapies in leukemia due to the reversible nature of epigenetic marks and amenability of chromatin-modifying enzymes to pharmacological inhibition.
How…
KOBENHAVNS UNIVERSITET
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