CORDIS Project
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This project focuses on the biophysical properties of a specific subtype of nicotinic acetylcholine receptors in human adrenal cells. It aims to explore their interactions with mitochondria and the regulation by reactive oxygen species, which could provide insights into neurological conditions such as Parkinson's disea…
Nicotinic acetylcholine receptors (nAChRs) containing the alpha6 subunit have been implicated in neurological and psychiatric conditions including Parkinson’s and nicotinic dependence.
Despite their potential therapeutic importance, little is known about the biophysical properties of these receptors in part because of their restricted tissue distribution and poor expression in heterologous systems.
Nevertheless, a recent report by Dr.
Albillos’ laboratory demonstrated that the alpha6beta4 subtyp…
UNIVERSIDAD AUTONOMA DE MADRID
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