CORDIS Project
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This project investigates cyclic nucleotides, key cellular messengers, to discover new signaling pathways in humans. By focusing on uncharacterized nucleotidyltransferases, the research aims to identify novel cyclic nucleotides that could lead to innovative therapeutic strategies, particularly in immune responses.
Survival of a cell depends on its ability to receive and process information coming from the environment.
Second messengers are the key transmitters of information that rapidly amplify the signal inside the cell.
Cyclic nucleotides (CNs) are the most diversified category of second messengers and are found in all organisms modulating diverse pathways. CNs are best studied in bacteria, where they have a variety of biological functions.
In humans, the only described cyclic di-nucleotide is cGAMP, w…
TECHNISCHE UNIVERSITAET MUENCHEN
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