CORDIS Project
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This project develops a novel method for attaching targeting ligands to nanocarriers for cancer drug delivery. By enhancing the interaction between drugs and cancer cells, it aims to improve treatment efficacy while reducing side effects, potentially transforming drug delivery and diagnostics.
Current clinically approved drug delivery systems, such as liposome, PEGylated liposome, and polymeric micelle, predominantly rely on passive accumulation within tumor tissues by diffusion through the defective tumor vessels during circulation.
The targeting efficacy toward cancer cells is very limited due to their inadequate interaction with cancer cells.
The attachment of targeting ligands to nanocarriers has demonstrated its effectiveness in enhancing binding affinity and, consequently, facil…
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