CORDIS Project
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The Ob_GLP1 project investigates how obesity affects brain circuits that regulate appetite, focusing on the glucagon-like peptide-1 receptor system. By exploring the neural mechanisms and potential therapeutic targets, the project aims to improve obesity treatment strategies through advanced imaging and molecular techn…
Obesity is a major health challenge in the EU and globally, and yet the best drug therapies achieve only modest reductions in weight loss and require life-long treatment.
To prevent and treat obesity it is crucial we understand the neural pathways controlling appetite and how they can be ‘hijacked’ therapeutically.
The brain glucagon-like peptide-1 (GLP1) system is a promising target. GLP1 receptor agonists (GLP1RAs) decrease food intake and bodyweight in obese patients, effects which are mediat…
THE UNIVERSITY OF BIRMINGHAM
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