CORDIS Project
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This project investigates the role of the p53 protein in the brain, particularly its influence on energy metabolism and potential as a treatment for obesity and diabetes. By manipulating p53 signaling in specific neurons, the research aims to uncover its effects on food intake and glucose regulation.
p53 is a transcriptional factor modulating numerous biological actions.
Although it is best known for its role in cancer development, it is now evident that it is implicated in metabolism.
More specifically, p53 modulates energy metabolism and homeostasis through their effects on adipocyte development and function.
However, nothing is known about the potential metabolic function of p53 in the central nervous system.Neuronal networks within the central nervous system play a crucial role in the re…
UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
UNIVERSIDAD DE SANTIAGO DE COMPOSTELA
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