CORDIS Project
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This project aims to develop a novel receptor to enhance the delivery of therapeutics across the blood-brain barrier, addressing challenges in treating brain-related illnesses. By creating a targeted delivery system that selectively expresses this receptor, the project seeks to improve the efficiency and safety of drug…
Many impairing illnesses raging from metastatic cancers to neurodegenerative diseases affect the brain.
Unfortunately, delivery of therapeutics to the brain is highly challenging due to the blood-brain barrier (BBB).
Despite decades of research, no safe and efficient strategy to overcome this barrier has reached clinical application.
Here we propose a concept that will revolutionize brain transport: creating a new orthogonal receptor to mediate transport across the BBB.
Numerous molecules have b…
INSTITUT QUIMIC DE SARRIA
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