CORDIS Project
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This project investigates the role of dopamine in the learning of new motor skills by utilizing advanced imaging and manipulation techniques in the mouse motor cortex. It aims to clarify how dopamine influences motor learning and cortical plasticity, enhancing our understanding of the underlying neuronal mechanisms.
Coordination, execution and learning of skilled movements strongly depend on motor cortex function, which, in turn, depends on the modulatory action of different neurotransmitters.
In particular, dopaminergic inputs to the motor cortex have been associated with synaptic plasticity, changes in cortical excitability and modulation of cortical motor maps.
The integrity of dopaminergic terminals is required for the acquisition of novel motor tasks, but not for the performance of already learned ones…
UNIVERSITE DE GENEVE
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