CORDIS Project
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This research focuses on the role of Rho GTPases in oligodendrocyte function and myelination, particularly in the context of multiple sclerosis. It aims to understand how these molecules affect cell interactions and remyelination.
Oligodendrocytes are the myelinating cells of the central nervous system (CNS).
The importance of myelination is illustrated by the neurological consequences caused by demyelination, the process or state resulting from the loss or destruction of myelin such as in multiple sclerosis (MS), the most frequent CNS chronic demyelinating disease.
Failure of remyelination is thought to be the major cause of MS disease progression and may be caused by the incapacity of oligodendrocyte progenitor cells (O…
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