CORDIS Project
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This research focuses on the outer membrane of Gram-negative bacteria, aiming to understand its organization and function. By studying protein interactions and dynamics in bacteria like Escherichia coli, the project seeks to uncover mechanisms that could lead to new antibiotic strategies.
The outer membrane (OM) of Gram-negative bacteria protects against environmental insult and is central to pathogenesis hence finding ways to disrupt its integrity is a route towards new antibiotics.
However, our understanding of OM biology is limited.
In particular, how the OM is organised is largely unknown.
My laboratory recently discovered spatiotemporal Outer Membrane Protein organisation (OMPorg) in Escherichia coli, a new organising principle that explains how OMPs are turned over.
We foun…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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