CORDIS Project
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This project explores the role of O-GlcNAcylation, a protein modification, in regulating RNA-binding proteins associated with amyotrophic lateral sclerosis (ALS). It aims to understand how this modification affects RNA processing, potentially providing insights into neurodegenerative diseases.
O-GlcNAcylation is a post-translational dynamic modification of proteins that is becoming more widely recognized as a modification that can protect proteins from pathological aggregation in neurodegenerative diseases.
However, it is unknown how this modification influences the RNA binding properties of the protein and its function.
In the proposed project I will study the O-Glc-NAcylation of RNA-binding proteins (RBPs) associated with amyotrophic lateral sclerosis (ALS), and its effects on the R…
KEMIJSKI INSTITUT
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Croatia, OSIJEK
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
United Kingdom, London
Type: Research institute
Activity type: Research Organisations
SME: No
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