CORDIS Project
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This project investigates the role of micro-RNAs in gene regulation and their link to cancer. It aims to analyze the biomolecular interactions involved in micro-RNA processing and explore the potential of using anti-sense oligonucleotides to inhibit oncogenic micro-RNAs as a novel cancer therapy.
Micro-RNAs are a recently identified class of small non-coding RNAs that have been shown to regulate the expression of up to 30% of human genes.
The contribution of miRNAs in gene regulation is gaining considerable attention, particularly given the growing links between miRNA mis-function or expression and disease.
Certain miRNAs have been demonstrated to display oncogenic-like phenotypic effects and their overexpression is heavily implicated in the development of cancers.
MiRNAs mature via a tw…
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