CORDIS Project
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This project investigates the role of delta opioid receptors in insulin secretion and metabolism, aiming to develop new therapeutic strategies for Type 2 diabetes and obesity. By combining advanced methodologies, the project seeks to understand how opioids influence metabolic processes, particularly in pancreatic beta…
Type 2 diabetes (T2D) and obesity are leading causes of morbidity and mortality, becoming a major burden on public health.
Failure to understand their pathophysiology has frustrated efforts to develop improved therapeutic strategies. T2D and obesity are complex polygenic disorders.
Genome-wide association studies have identified hundreds of loci associated with metabolic traits, but they have not led to promising new drug targets, so far.
In contrast, the identification and characterization of r…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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