CORDIS Project
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This project investigates the role of Major Histocompatibility Complex (MHC) genes in the immune responses of wild songbirds. By studying MHC diversity and its effects on survival, it aims to enhance understanding of immunity in natural populations.
The Major Histocompatibility Complex (MHC) genes are intensively studied genes in association with disease resistance. MHC proteins are essential for initiating every adaptive immune response and MHC is probably the most extreme example of how selection from a wide range of pathogens maintains high diversity in host immunity genes.
However, the functions of the MHC proteins are only known in humans and model organisms, species that cannot be studied under natural conditions.
There is therefore a…
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