CORDIS Project
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This project investigates the neural circuits responsible for locomotion using optogenetics to manipulate specific neurons. It aims to understand sensory feedback mechanisms and improve recovery after spinal cord injuries by studying the role of cerebrospinal fluid-contacting neurons.
Locomotion relies on neural networks called central pattern generators (CPGs) that generate periodic motor commands for rhythmic movements.
The manipulation of electrical activity and cell signaling in specific neuron type using light gated receptors enables us today to dissect the specific neuronal circuits forming the CPGs, and understand the dynamic role of sensory inputs in awake behaving animals.During my work in UC Berkeley, I developed the use of light gated receptors in vivo (Szobota 200…
INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE
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