CORDIS Project
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This project investigates how leader cells influence the collective movement of groups of epithelial cells, which is crucial for processes like wound healing and cancer spread. Using optogenetics, the project aims to control cell behavior with light, providing insights into cell interactions and migration dynamics.
Emergent collective behaviours such as flocks and waves are a hallmark of biological active matter, and occur prominently also in large groups of migrating epithelial cells, where they are involved in fundamental biological processes such as wound healing, morphogenesis and cancer cell invasion.
Physical forces transduced between cells and arising between cells and the extracellular matrix (ECM) play an integral role in orchestrated multicellular phenomena.
Another integral contribution is given…
FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA
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