CORDIS Project
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This project focuses on developing light-responsive RNA molecules to control cellular processes. By creating modular RNA assemblies that respond to light, it aims to enhance optogenetic techniques, allowing researchers to analyze biomolecule functions in real-time across various biological systems.
Light-sensitive channel proteins have attracted much attention as functional molecules, as they possess unique conformations and functions depending on their respective irradiation states.
Embedding these proteins in heterogeneous cellular frameworks enabled to gain light-control of cellular and in particular neuronal behaviour.
However to date, optogenetic solutions that address endogenous, intracellular biomolecules in a universal fashion remain elusive.
The project will apply design and selec…
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