CORDIS Project
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OrAIOn systematically studies how oncology drugs affect vaccine responses in cancer patients. By utilizing high-throughput screening and AI modeling, the project aims to create a comprehensive database of drug-vaccine interactions, ultimately improving vaccination strategies for cancer patients.
Infectious diseases caused >2 million deaths in 2019 (pre-COVID-19).
Cancer patients die more often from infections than healthy individuals and are less effectively protected by vaccines.
Several studies link oncology drugs to altered vaccine responses.
While designed to inhibit tumor progression, these drugs also affect immune functions and thus may interfere with vaccine responses – for better or worse. A systematic analysis of this problem has so far been hampered by a lack of suitable model…
EBERHARD KARLS UNIVERSITAET TUEBINGEN
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