CORDIS Project
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This project aims to enhance the understanding of peptide-mediated protein interactions, which are crucial for cellular regulation. It combines computational modeling and experimental validation to explore how these interactions can be manipulated for therapeutic applications.
Peptide-mediated protein interactions are emerging as key regulators of many important regulatory processes in the cell.
Short motifs, usually embedded into disordered regions of the protein, interact with specific sets of protein partners in a transient way and allow efficient and malleable propagation of signals towards their targets.
While regular protein interactions have been intensively studied, many aspects of peptide-mediated interactions have not yet been elucidated.The aim of this prop…
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