CORDIS Project
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Organ-VIP focuses on improving the interpretation of genetic variants in colorectal cancer by developing a functional assay platform using CRISPR-edited organoids. This project aims to enhance the clinical relevance of genetic testing and facilitate high-throughput evaluations of cancer-related genes.
Implementation of next generation sequencing to genetic diagnosis and precision medicine has revolutionized the fields of hereditary cancer and oncology, increasing exponencially the identification of genetic variants of uncertain significance.
Their classification is one of the most relevant and urgent challenges we face, since decision-making in the clinics depends on it.
Evidence obtained from empirical functional studies is essential to reach a definitive classification; however, clinical re…
FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE
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