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This research examines the molecular processes behind cell differentiation in choanoflagellates, aiming to understand the evolutionary origins of animal development. It investigates chromatin regulation and gene expression during temporal differentiation.
During animal development the process of cell differentiation gives rise to terminally differentiated cell types with cell-type-specific gene expression programs.
In the most closely related group to animals, the choanoflagellates, cell differentiation occurs but cells do not commit irreversibly to specific fates.
Instead, they transition through cell identities as they progress through their life cycle, known as temporal cell differentiation.
Animal cell differentiation is thought to have evolv…
UNIVERSITY OF GALWAY
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