CORDIS Project
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The ORTHOCAT project aims to improve cancer treatment by developing riboflavin-based systems that activate platinum-based anticancer drugs specifically within mitochondria. This approach seeks to enhance the effectiveness of photodynamic therapy while reducing side effects associated with traditional treatments.
New cancer care methodologies with fewer side effects and no need for major surgery are required to enhance patient wellbeing.
Photodynamic Therapy (PDT) partially accomplishes such mission employing light and a photosensitizer.
Nevertheless, the PDT mechanism of action intimately depends on oxygen, which limits its efficacy, particularly in hypoxic solid tumours.
Promising strategies to improve the impact of PDT in the clinics currently involve the design of photoactivatable transition metal co…
FUNDACION DONOSTIA INTERNATIONAL PHYSICS CENTER
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