CORDIS Project
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This project investigates how oxygen levels affect the behavior of cardiovascular progenitor cells during heart development. It aims to understand the role of hypoxia in regulating cell growth and differentiation, potentially leading to new strategies in cardiovascular therapies.
Cardiogenesis is a complex process that involves different cell types that have to mature to form the final functional heart compartments.
Isl1 cardiovascular progenitors label the “second heart field” and contribute to myocardial, smooth muscle and endothelial structures of the heart.
These progenitors have been extensively studied but little is know about the extracellular signals mediating their cell fate decisions and biology. A more recent group of cardiovascular progenitors arising from th…
CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.)
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