CORDIS Project
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This project investigates the role of cholesterol metabolites in the immune response, particularly in multiple sclerosis. It focuses on how specific regulatory T cells are influenced by these metabolites, aiming to identify new therapeutic targets for autoimmune diseases.
Accumulating evidence indicates that cholesterol metabolism plays a major role during acquired immune response.
Cholesterol metabolites oxysterols have recently been proposed to be involved in the pathogenesis of multiple sclerosis (MS), considered to be the first cause of neurologic disability among young adults in occidental countries. MS is characterized by demyelination throughout the central nervous system associated with inflammatory infiltrates of lymphocytic and mononuclear cell.
The bal…
UNIVERSITE DE GENEVE
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